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| Status |
Public on Mar 20, 2020 |
| Title |
Lipopolysaccharide induced inflammatory response in mouse intestinal epithelial cells |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Lipopolysaccharides (LPS) can lead to a lethal endotoxemia, which is a systemic inflammatory response syndrome (SIRS) characterized by a systemic release of cytokines, such as TNF. Endotoxemia is studied intensely, as a model system of gram-negative infections. LPS- as well as TNF-induced SIRS involve a strong induction of pro-inflammatory genes. In this study we investigate the response of the intestinal epithelium cells (IECs) ot LPS and may produce pro-inflammatory cytokines or suffer cell death.
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| |
|
| Overall design |
6 samples total, 3 LPS stimulated sampels, 3 PBS controls. All samples from the same condition are biological replicates
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| |
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| Contributor(s) |
Van Looveren K, Timmermans S, Vandewalle J, Libert C |
| Citation(s) |
32383538 |
| |
| Submission date |
Nov 04, 2019 |
| Last update date |
Jun 10, 2020 |
| Contact name |
Steven Timmermans |
| Organization name |
VIB-UGent
|
| Street address |
Technologiepark 71
|
| City |
Gent |
| ZIP/Postal code |
9052 |
| Country |
Belgium |
| |
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| Platforms (1) |
| GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
|
| Samples (6)
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| Relations |
| BioProject |
PRJNA587504 |
| SRA |
SRP228555 |
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