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Series GSE139653 Query DataSets for GSE139653
Status Public on Jun 22, 2020
Title Comprehensive analysis of circRNA expression profiles and circRNA-associated ceRNA networks in age-related changes of mouse thymus
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Non-coding RNA profiling by high throughput sequencing
Summary Our findings further expand the current knowledge regarding the biology of ceRNAs and their regulatory roles in thymic development and involution process. These newly discovered networks provide more ideas for further research about age-related thymic changes in the future.
Overall design we used miRNA sequencing and LncRNA sequencing to detect several time points in mouse thymic development (2, 6 weeks old and 3 months old) to study the underlying biological mechanisms in the rapid development of the thymus after birth (from 2 weeks old to 6 weeks old) and the subsequent decline process (from 6 weeks old to 3 months old).
Contributor(s) Zhang W, Wan J, Li W, Ma N
Citation(s) 32307889
Submission date Oct 31, 2019
Last update date Jun 22, 2020
Contact name Wen Ting Li
Organization name Shenzhen PKU-HKUST Medical Center
Street address No,1120,LianHua Road,FuTian District
City Shenzhen
ZIP/Postal code 518000
Country China
Platforms (2)
GPL17021 Illumina HiSeq 2500 (Mus musculus)
GPL24247 Illumina NovaSeq 6000 (Mus musculus)
Samples (12)
GSM4145362 miRNA T_2W_1
GSM4145363 lncRNA T_2W_1
GSM4145364 miRNA T_2W_2
BioProject PRJNA586829
SRA SRP227793

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Supplementary file Size Download File type/resource
GSE139653_circRNA.expression.txt.gz 169.4 Kb (ftp)(http) TXT
GSE139653_lncRNA.expression.txt.gz 400.4 Kb (ftp)(http) TXT
GSE139653_mRNA.expression.txt.gz 28.9 Mb (ftp)(http) TXT
GSE139653_miRNA.expression.txt.gz 60.7 Kb (ftp)(http) TXT
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