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Series GSE139076 Query DataSets for GSE139076
Status Public on May 04, 2020
Title circRNA expression in METTL3 and YTHDC1 KNOCK-DOWN conditions
Organism Homo sapiens
Experiment type Non-coding RNA profiling by high throughput sequencing
Summary Through an siRNA based approach, we investigated the effect of the knock-down of METTL3 and YTHDC1 on circRNAs expression in HeLa cells
Overall design Total RNA from HeLa cells treated either with siRNA against METTL3 (two biological replicates) and control siRNA (one biological replicate), together with total RNA from HeLa cells treated with a siRNA against YTHDC1 (two biological replicates) and control siRNA (two biological replicates), was analyzed using Illumina Novaseq6000.
Contributor(s) Di Timoteo G, Dattilo D, Guarnacci M, Colantoni A, CentrĂ³n-Broco A, Rossi F, Morlando M, Bozzoni I
Citation(s) 32402287
Submission date Oct 18, 2019
Last update date Aug 04, 2020
Contact name Gaia Di Timoteo
Organization name University of Rome "La Sapienza"
Street address piazza Aldo Moro 5
City Rome
State/province RM
ZIP/Postal code 00185
Country Italy
Platforms (1)
GPL24676 Illumina NovaSeq 6000 (Homo sapiens)
Samples (7)
GSM4128757 HeLa cells, METTL_SCR_A
GSM4128758 HeLa cells, METTL3_KD_A
GSM4128759 HeLa cells, METTL3_KD_B
BioProject PRJNA578279
SRA SRP226173

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Supplementary file Size Download File type/resource
GSE139076_RAW.tar 2.2 Mb (http)(custom) TAR (of TXT)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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