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| Status |
Public on Jun 23, 2021 |
| Title |
RNA-seq analysis of human pancreas cell line SU8686 treated with DOT1L inhibitor (SGC0946) or DMSO |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
To understand the pathway alteration associated with DOT1L inhibition, we performed RNA-seq analysis of DOT1L inhibitor treated human pancreas cell line SU8686. We reported the changed pathways.
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| Overall design |
The SU8686 cells were treated with 20 μM SGC0946 or DMSO for 72 hr (triplicate)
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| Contributor(s) |
Liu Z, Liu Y, Qian L, Jiang S, Gai X, Ye S, Chen Y, Wang X, Zhai L, Xu J, Pu C, Li J, He F, Huang M, Tan M |
| Citation(s) |
34375582 |
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| Submission date |
Oct 18, 2019 |
| Last update date |
Sep 22, 2021 |
| Contact name |
Zhiwei Liu |
| E-mail(s) |
lzw150@outlook.com
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| Organization name |
Chinese Academy of Sciences
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| Street address |
Zuchongzhi Road 555
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| City |
Shanghai |
| ZIP/Postal code |
201203 |
| Country |
China |
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| Platforms (1) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA578266 |
| SRA |
SRP226165 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE139070_transcript.fpkm.matrix.annot.xls.gz |
21.4 Mb |
(ftp)(http) |
XLS |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data are available on Series record |
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