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Series GSE138014 Query DataSets for GSE138014
Status Public on Sep 26, 2022
Title Enhancing Acsl4 in absence of mTORC2/Rictor drove β-cell dedifferentiation via inhibiting FoxO1 and promoting ROS production
Organism Mus musculus
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary We here identified Acsl4, a new target of mTORC2, could rescue the impaired β cell proliferation, but not deficient insulin secretion induced by loss of Rictor.
Overall design ex vivo overexpression Acsl4 in βRicKO mice
Contributor(s) Cui C, Gu Y
Citation(s) 34455055
Submission date Sep 25, 2019
Last update date Dec 30, 2022
Contact name canqi cui
Organization name shanghai national reaearch center for endocrine and metabolic diseases
Street address 197 Ruijin 2nd Road
City Shanghai
ZIP/Postal code 20025
Country China
Platforms (1)
GPL24247 Illumina NovaSeq 6000 (Mus musculus)
Samples (6)
GSM4096655 Con+Ad-GFP-1(WT)
GSM4096656 Con+Ad-GFP-2(WT2)
GSM4096657 βRicKO+Ad-GFP-1(KO1)
BioProject PRJNA574153
SRA SRP223227

Download family Format
SOFT formatted family file(s) SOFTHelp
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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE138014_RAW.tar 609.0 Mb (http)(custom) TAR (of BED, BW)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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