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| Status |
Public on Sep 18, 2020 |
| Title |
Transcriptomic Characterization of neuroblastoma by Single Cell RNA Sequencing |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Neuroblastoma (NB) is the most common malignant solid tumor in the abdomen of children, with high degree of malignancy, poor prognosis and unknown pathogenesis. So we aim to investigate intra-tumor heterogeneity of neuroblastoma at single cell resolution.
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| |
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| Overall design |
Single cell mRNA profiles of sixteen primary tumors from sixteen patients with neuroblastoma, four adrenal tissue and two embryos from six aborted fetus were generated by 10X Genomics plartform, without technical replication, and sequenced by NovaSeq 6000 (Illumina)
|
| Web link |
https://www.cell.com/cancer-cell/pdf/S1535-6108(20)30425-6.pdf
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| |
|
| Contributor(s) |
Dong R, Wang J, Li K, Dong K, Zhan Y, Ye C |
| Citation(s) |
32946775 |
| Submission date |
Sep 20, 2019 |
| Last update date |
Mar 12, 2021 |
| Contact name |
rui Dong |
| E-mail(s) |
rdong@fudan.edu.cn
|
| Organization name |
Department of Pediatric Surgery, Children’s Hospital of Fudan University, and Shanghai Key Laboratory of Birth Defect
|
| Street address |
399 Wan Yuan Road
|
| City |
Shanghai |
| ZIP/Postal code |
201102 |
| Country |
China |
| |
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| Platforms (1) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
| Samples (22)
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| Relations |
| BioProject |
PRJNA573097 |
| SRA |
SRP222837 |
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