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Series GSE137779 Query DataSets for GSE137779
Status Public on Sep 01, 2022
Title Histone-acetyl Epigenome Regulates TGF-β Pathway-associated Chemoresistance in Colorectal Cancer
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary The global up-regulation of histone acetylation modification after the activation of the TGF-β signaling pathway raised the possibility that the differential expression of specific histone acetyltransferases or histone deacetylases may involve in the modulation of TGF-β-associated chemoresistance in CRC. To test this hypothesis, high-throughput mRNA sequencing (RNA-Seq) was performed to compare the expression profile between SW480 cells treated with or without TGF-β1.
Overall design RNA-seq was performed in SW480 colorectal cancer cells afterTGF-β1 treatment
Contributor(s) Xianglong T
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Submission date Sep 20, 2019
Last update date Sep 03, 2022
Contact name Haoyan Chen
Organization name Renji Hospital
Street address 145 Shandong Road
City Shanghai
State/province Shanghai
ZIP/Postal code 200001
Country China
Platforms (1)
GPL21290 Illumina HiSeq 3000 (Homo sapiens)
Samples (6)
GSM4087746 Control 1
GSM4087747 Control 2
GSM4087748 Control 3
BioProject PRJNA573050
SRA SRP222778

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE137779_RAW.tar 1.2 Mb (http)(custom) TAR (of TXT)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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