|
| Status |
Public on Sep 01, 2022 |
| Title |
Histone-acetyl Epigenome Regulates TGF-β Pathway-associated Chemoresistance in Colorectal Cancer |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
The global up-regulation of histone acetylation modification after the activation of the TGF-β signaling pathway raised the possibility that the differential expression of specific histone acetyltransferases or histone deacetylases may involve in the modulation of TGF-β-associated chemoresistance in CRC. To test this hypothesis, high-throughput mRNA sequencing (RNA-Seq) was performed to compare the expression profile between SW480 cells treated with or without TGF-β1.
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| |
|
| Overall design |
RNA-seq was performed in SW480 colorectal cancer cells afterTGF-β1 treatment
|
| |
|
| Contributor(s) |
Xianglong T |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Sep 20, 2019 |
| Last update date |
Sep 03, 2022 |
| Contact name |
Haoyan Chen |
| Organization name |
Renji Hospital
|
| Street address |
145 Shandong Road
|
| City |
Shanghai |
| State/province |
Shanghai |
| ZIP/Postal code |
200001 |
| Country |
China |
| |
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| Platforms (1) |
| GPL21290 |
Illumina HiSeq 3000 (Homo sapiens) |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA573050 |
| SRA |
SRP222778 |
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