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Series GSE136875 Query DataSets for GSE136875
Status Public on Aug 26, 2022
Title Assessment of the stabilty of Treg cell subsets in the bone marrow [targeted Bisulfite-seq]
Organism Mus musculus
Experiment type Methylation profiling by high throughput sequencing
Summary We analyzed the methlation status of bone marrow conventional T cells, pTregs, tTregs, Tregs induced by bone marrow Aire-expressing cells, and in vitro-induced Tregs
Overall design 6.5TCR (HA-specific CD4) T cells were transferred into Aire-HA host and bone marrow T cell subsets were sorted 14 days post transfer for comparison of their methylation status of TSDR and Treg-specific signature genes
Contributor(s) Chen C, Delacher M, Imbusch CD, Feuerer M, Beckhove P
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Submission date Sep 04, 2019
Last update date Aug 27, 2022
Contact name Philipp Beckhove
Organization name Regensburg Center for Interventional Immunology
Street address Franz-Josef-Strauss-Allee 11
City Regensburg
ZIP/Postal code 93053
Country Germany
Platforms (1)
GPL16417 Illumina MiSeq (Mus musculus)
Samples (15)
GSM4060088 Bisulfite-seq_Donor 6.5TCR T cells which were not converted to Tregs, rep1
GSM4060089 Bisulfite-seq_Donor 6.5TCR T cells which were not converted to Tregs, rep2
GSM4060090 Bisulfite-seq_Donor 6.5TCR T cells which were not converted to Tregs, rep3
This SubSeries is part of SuperSeries:
GSE136650 Induction of autoreactive regulatory T cells through promiscuous gene expression by bone marrow-resident Aire+ antigen-presenting cells
BioProject PRJNA563903
SRA SRP220343

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE136875_RAW.tar 30.0 Kb (http)(custom) TAR (of TXT)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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