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| Status |
Public on Jan 17, 2021 |
| Title |
LINE-1 promoter methylation analysis in brain development |
| Organism |
Mus musculus |
| Experiment type |
Methylation profiling by high throughput sequencing
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| Summary |
We performed methylation analisys of L1MdTf sequence and IAPLTR1a during mouse brain development, in cortex, hippocampus and cerebellum at different developmental stages (E15.5, E18.5, P0, P3, P14). We defined specific waves of methylation for L1MdTf promoter.
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| Overall design |
Bisulfite conversion based methylation analysis of L1MdTf and IAPLTR1a elements during mouse brain development. We analyzed cerebellum, cortex and hippocampus at 5 different developmental stages E15.5, E18.5, P0, P3 and P14. 4 mice at each developmental stage were analyzed.
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| Contributor(s) |
Bodega B, Fumagalli M |
| Citation(s) |
33541338 |
| Submission date |
Sep 04, 2019 |
| Last update date |
Feb 16, 2021 |
| Contact name |
Beatrice Bodega |
| E-mail(s) |
bodega@ingm.org
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| Organization name |
INGM Istituto Nazionale Genetica Molecolare
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| Street address |
Via Francesco Sforza 35
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| City |
Milan |
| ZIP/Postal code |
20122 |
| Country |
Italy |
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| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
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| Samples (120)
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| Relations |
| BioProject |
PRJNA563846 |
| SRA |
SRP220293 |
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