|
| Status |
Public on Sep 17, 2020 |
| Title |
Dissection of FUS domains involved in regulation of SnRNP70 gene expression |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
To identify FUS regulated genes and its dependency of snRNP70, the gene expression profiles in neurons expressing the Gly-rich domain deleted FUS mutant coupled with Snrnp70 gene knock down were analyzed.
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| |
|
| Overall design |
Mouse ES cell derived neurons were infected with lentivirus encoding FLAG-tagged Gly-rich domain deleted FUS, shRNA for Snrnp70 gene or both, and analysed the gene expression by RNA-seq.
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| |
|
| Contributor(s) |
Nakaya T |
| Citation(s) |
32915994 |
| |
| Submission date |
Aug 30, 2019 |
| Last update date |
Oct 22, 2020 |
| Contact name |
Tadashi Nakaya |
| E-mail(s) |
tadashi.nakaya@iuhw.ac.jp
|
| Organization name |
International University of Health and Welfare
|
| Department |
School of Pharmacy at Fukuoka
|
| Street address |
137-1 Enokizu
|
| City |
Okawa |
| State/province |
Fukuoka |
| ZIP/Postal code |
8318501 |
| Country |
Japan |
| |
|
| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
|
| Samples (8)
|
|
| Relations |
| BioProject |
PRJNA563002 |
| SRA |
SRP219860 |
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