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Series GSE136663 Query DataSets for GSE136663
Status Public on Sep 17, 2020
Title Dissection of FUS domains involved in regulation of SnRNP70 gene expression
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary To identify FUS regulated genes and its dependency of snRNP70, the gene expression profiles in neurons expressing the Gly-rich domain deleted FUS mutant coupled with Snrnp70 gene knock down were analyzed.
Overall design Mouse ES cell derived neurons were infected with lentivirus encoding FLAG-tagged Gly-rich domain deleted FUS, shRNA for Snrnp70 gene or both, and analysed the gene expression by RNA-seq.
Contributor(s) Nakaya T
Citation(s) 32915994
Submission date Aug 30, 2019
Last update date Oct 22, 2020
Contact name Tadashi Nakaya
Organization name International University of Health and Welfare
Department School of Pharmacy at Fukuoka
Street address 137-1 Enokizu
City Okawa
State/province Fukuoka
ZIP/Postal code 8318501
Country Japan
Platforms (1)
GPL24247 Illumina NovaSeq 6000 (Mus musculus)
Samples (8)
GSM4054741 mmu_siLuc_1
GSM4054742 mmu_siLuc_2
GSM4054743 mmu_siSnrnp70_1
BioProject PRJNA563002
SRA SRP219860

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SOFT formatted family file(s) SOFTHelp
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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE136663_mmu_gene_count.txt.gz 288.3 Kb (ftp)(http) TXT
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