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Series GSE136262 Query DataSets for GSE136262
Status Public on Aug 24, 2019
Title A combined epigenome- and transcriptome-wide association study of the oral masticatory mucosa assigns CYP1B1 a central role for epithelial health in smokers
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary Healthy ex vivo biopsies from masticatory mucosa from 17 current and 21 never smokers were analysed using whole transcriptome RNA sequencing (16 mio reads/sample), showing significantly increased expression of CYP1B1 in smokers compared to non-smokers (p = 2.2 × 10−14), together with 13 significantly upregulated transcripts. Six transcripts were significantly downregulated.
Overall design mRNA profiles of ex vivo masticatory mucosa from 17 current smokers and 21 never smokers
Contributor(s) Richter GM, Schaefer AS
Citation(s) 31331382
Submission date Aug 23, 2019
Last update date Aug 29, 2019
Contact name Gesa Marijke Richter
Organization name Charité - University Medicine Berlin
Street address Assmannshauser Str. 4-6
City Berlin
ZIP/Postal code 14197
Country Germany
Platforms (1)
GPL21290 Illumina HiSeq 3000 (Homo sapiens)
Samples (38)
GSM4043633 sample1_nonsm
GSM4043634 sample2_nonsm
GSM4043635 sample3_nonsm
BioProject PRJNA561777
SRA SRP219430

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE136262_ProcessedData_lengthscaledTPM.txt.gz 2.3 Mb (ftp)(http) TXT
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Raw data are available in SRA
Processed data are available on Series record

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