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Series GSE136029 Query DataSets for GSE136029
Status Public on Aug 20, 2019
Title The effect of attenuated Salmonella typhimurium on the tumor epithelium in mouse colorectal cancer model
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary Bacterial cancer therapy (BCT) shows great promise for treatment of solid tumors, yet basic mechanisms of bacterial-induced tumor suppression remain undefined. We aimed to better understand the tumor epithelium-targeted mechanisms of BCT by using mouse models of intestinal tumorigenesis to assess the effectiveness and mechanisms of treatment with aromatase A-deficient Salmonella typhimurium (STm) delivered by oral gavage.
Overall design RNAseq using normal colon tissue or colon tumor induced by AOM/DSS, treated or non-treated with aromatase A-deficient STm delivered by oral gavage
Contributor(s) Oda H, Maslowski KM
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Submission date Aug 19, 2019
Last update date Aug 22, 2019
Contact name Daniel L Kastner
Organization name NIH
Department NHGRI
Street address 9000 Rockville Pike
City Bethesda
State/province MD
ZIP/Postal code 20892
Country USA
Platforms (1)
GPL18480 Illumina HiSeq 1500 (Mus musculus)
Samples (17)
GSM4039602 Normal_NonTreat_1
GSM4039603 Normal_NonTreat_2
GSM4039604 Normal_NonTreat_3
BioProject PRJNA560971
SRA SRP218864

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Supplementary file Size Download File type/resource
GSE136029_FPKMall.190819.arr.txt.gz 1.1 Mb (ftp)(http) TXT
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Raw data are available in SRA
Processed data are available on Series record

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