GEO Logo
   NCBI > GEO > Accession DisplayHelp Not logged in | LoginHelp
GEO help: Mouse over screen elements for information.
Series GSE135921 Query DataSets for GSE135921
Status Public on Jan 31, 2020
Title RNAseq of renal CD64+CD11b+F4/80hi from adult mice after cisplatin-induced acute kidney injury
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary We use bulk RNA sequencing of sorted cells to characterize the gene expression profiles of renal MHCII+/-D11b+F4/80hi cells 72 hours after cisplatin-induced acute kidney injury (AKI). F4/80hi cells are activated after cisplatin induced AKI and start to downregulate MHCII on transcriptional level. Downregulation of MHCII is probably caused by a downregulation/inhibition of its most important transcriptional activator Ciita
Overall design bulk RNA sequencing of sorted murine renal F4/80hi cells before and after cisplatin induced acute kidney injury
Contributor(s) Rambichler S, Salei N, Schraml BU
Citation(s) 31932472
Submission date Aug 17, 2019
Last update date Jun 10, 2020
Contact name Barbara Schraml
Organization name LMU Munich
Street address GroƟhaderner Strasse 9
City Planegg
ZIP/Postal code 82152
Country Germany
Platforms (1)
GPL18480 Illumina HiSeq 1500 (Mus musculus)
Samples (8)
GSM4037973 BS51_MHCIIpos_F480hi_ctrl
GSM4037974 BS52_MHCIIpos_F480hi_ctrl
GSM4037975 BS53_MHCIIneg_F480hi_AKI
BioProject PRJNA560645
SRA SRP218653

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE135921_RAW.tar 4.8 Mb (http)(custom) TAR (of TAB, TXT)
GSE135921_TPM_all_samples_values.csv.gz 377.8 Kb (ftp)(http) CSV
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file
Processed data are available on Series record

| NLM | NIH | GEO Help | Disclaimer | Accessibility |
NCBI Home NCBI Search NCBI SiteMap