GEO Logo
   NCBI > GEO > Accession DisplayHelp Not logged in | LoginHelp
GEO help: Mouse over screen elements for information.
Series GSE134980 Query DataSets for GSE134980
Status Public on Jul 27, 2019
Title RBMX preferentially associates with repetitive DNAs along with RPA
Organism Homo sapiens
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary To characterize the binding sites of RBMX and RPA on chromatin, 293T cells were treated with CPT and binding profiles were obtained by ChIP-seq assay. RBMX ChIP-seq profile was highly correlated with RPA ChIP-seq profile, both showing strong peaks at centromeres. To characterize the occupancy sites bound by both RBMX and RPA, we annotated their shared peaks. The results showed that these sequences are mostly enriched on repetitive DNAs including rRNA, simple repeats and satellite DNAs.
Overall design Examination of RBMX and RPA1 binding profiles in 293T cells.
Contributor(s) Zheng T, Zhao Y
Citation(s) 32494026
Submission date Jul 26, 2019
Last update date Jun 27, 2020
Contact name Tian Zheng
Organization name Sun Yat-sen University
Street address No. 135 West Xingang Road
City Guangzhou
ZIP/Postal code 510275
Country China
Platforms (2)
GPL23227 BGISEQ-500 (Homo sapiens)
GPL24676 Illumina NovaSeq 6000 (Homo sapiens)
Samples (6)
GSM3983070 RPA1_ChIPSeq
GSM3983071 RBMX_ChIPSeq
GSM4460555 Input-RBMX-rep2
BioProject PRJNA556911
SRA SRP216549

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE134980_RAW.tar 50.0 Kb (http)(custom) TAR (of TXT)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

| NLM | NIH | GEO Help | Disclaimer | Accessibility |
NCBI Home NCBI Search NCBI SiteMap