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Series GSE134902 Query DataSets for GSE134902
Status Public on Aug 19, 2019
Title scRNAseq transcriptome analysis of developing regulatory T cells and precursors in the thymus
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary We analyzed the individual transcriptomes of thymic Treg cells (CD4+Foxp3+), their immediate precursors (CD25+CD4+Foxp3-) and mature CD4 single positive thymocytes (CD4+Foxp3-CD25-CD62L+CD24-).
Overall design To gain insight into characteristic features of thymocytes producing IL-2 in situ, single-cell RNA sequencing data was collected from mature CD25-Foxp3-CD4SP, CD25+Foxp3- and Foxp3+ CD4SP thymocytes.
Contributor(s) Hemmers S, Schizas M, Azizi E, Dikiy S, Zhong Y, Feng Y, Altan-Bonnet G, Rudensky AY
Citation(s) 31434685
Submission date Jul 25, 2019
Last update date Nov 21, 2019
Contact name Elham Azizi
Organization name Memorial Sloan Kettering Cancer Center
Street address 417 E 68th St Z1141
City New York
State/province NY
ZIP/Postal code 10065
Country USA
Platforms (1)
GPL24247 Illumina NovaSeq 6000 (Mus musculus)
Samples (3)
GSM3978654 CD4plusCD25plus
GSM3978655 Foxp3plus
GSM3978656 MatureCD4SP
BioProject PRJNA556716
SRA SRP216429

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Supplementary file Size Download File type/resource
GSE134902_RAW.tar 25.6 Mb (http)(custom) TAR (of CSV)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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