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Series GSE134612 Query DataSets for GSE134612
Status Public on Sep 14, 2020
Title Molecular mechanisms of transcriptional regulation by the nuclear zinc-finger protein ZFAT in HEK293 cells
Organism Homo sapiens
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary ZFAT is a nuclear protein that harbors putative DNA-binding domains. Studies in mice have shown that ZFAT plays a critical role in survival and differentiation in T cells. However, molecular mechanisms whereby ZFAT regulates gene expression programs in human cells remain poorly unknown. We here identify the direct target genes of ZFAT in HEK293 human embryonic kidney cells through combination of chromatin immunoprecipitation with sequencing and transcriptional profiling.
Overall design ChIPseq data were obtained for a zinc-finger transcription factor ZFAT to elucidate the functions of ZFAT in HEK293 cells.
Contributor(s) Ishikura S, Tsunoda T, Nakabayashi K, Shirasawa S
Citation(s) 32997115
Submission date Jul 22, 2019
Last update date Nov 16, 2020
Contact name Kazuhiko Nakabayashi
Organization name National Research Institute for Child Health and Development
Department Department of Maternal-Fetal Biology
Street address 2-10-1 Okura
City Setagaya
State/province Tokyo
ZIP/Postal code 157-8535
Country Japan
Platforms (1)
GPL18460 Illumina HiSeq 1500 (Homo sapiens)
Samples (2)
GSM3958116 HEK293-mock_antiHA-Ab
GSM3958117 HEK293-pEB-ZFAT-HA_antiHA-Ab
BioProject PRJNA555854
SRA SRP215861

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Supplementary file Size Download File type/resource
GSE134612_16vs15_peaks.narrowPeak.gz 314.3 Kb (ftp)(http) NARROWPEAK
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