|
Status |
Public on Sep 18, 2019 |
Title |
The activation of IL-1 induced enhancers depends on TAK1 kinase activity and NF-KB p65 (ATAC-Seq) |
Organism |
Homo sapiens |
Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
Summary |
The inflammatory gene response requires activation of the protein kinase TAK1, but it is currently unknown how TAK1-derived signals coordinate transcriptional programs in the genome. We determined the chromatin accessibilty at the genome-wide level by ATAC-seq experiments.
|
|
|
Overall design |
ATAC-seq in KB cells under different treatment conditions
|
|
|
Contributor(s) |
Bartkuhn M, Kracht M |
Citation(s) |
31701553 |
|
Submission date |
Jul 17, 2019 |
Last update date |
Jan 14, 2020 |
Contact name |
Marek Bartkuhn |
E-mail(s) |
marek.bartkuhn@gen.bio.uni-giessen.de
|
Organization name |
Justus-Liebig-University Giessen
|
Department |
Biomedical Informatics and Systems Medicine
|
Street address |
Aulweg 132
|
City |
Giessen |
State/province |
Hessen |
ZIP/Postal code |
35392 |
Country |
Germany |
|
|
Platforms (1) |
GPL11154 |
Illumina HiSeq 2000 (Homo sapiens) |
|
Samples (4)
|
|
This SubSeries is part of SuperSeries: |
GSE134436 |
Characterization of IL-1α–responsive enhancers and of IL-1α -mediated changes in chromatin topology. |
|
Relations |
BioProject |
PRJNA555426 |
SRA |
SRP215525 |