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Series GSE134434 Query DataSets for GSE134434
Status Public on Sep 18, 2019
Title The activation of IL-1 induced enhancers depends on TAK1 kinase activity and NF-KB p65 (ATAC-Seq)
Organism Homo sapiens
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary The inflammatory gene response requires activation of the protein kinase TAK1, but it is currently unknown how TAK1-derived signals coordinate transcriptional programs in the genome. We determined the chromatin accessibilty at the genome-wide level by ATAC-seq experiments.
 
Overall design ATAC-seq in KB cells under different treatment conditions
 
Contributor(s) Bartkuhn M, Kracht M
Citation(s) 31701553
Submission date Jul 17, 2019
Last update date Jan 14, 2020
Contact name Marek Bartkuhn
E-mail(s) marek.bartkuhn@gen.bio.uni-giessen.de
Organization name Justus-Liebig-University Giessen
Department Biomedical Informatics and Systems Medicine
Street address Aulweg 132
City Giessen
State/province Hessen
ZIP/Postal code 35392
Country Germany
 
Platforms (1)
GPL11154 Illumina HiSeq 2000 (Homo sapiens)
Samples (4)
GSM3946565 ATAC-seq KB
GSM3946566 ATAC-seq KB IL1
GSM3946567 ATAC-seq KB 5Z
This SubSeries is part of SuperSeries:
GSE134436 Characterization of IL-1α–responsive enhancers and of IL-1α -mediated changes in chromatin topology.
Relations
BioProject PRJNA555426
SRA SRP215525

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE134434_RAW.tar 655.5 Mb (http)(custom) TAR (of BIGWIG)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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