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| Status |
Public on May 24, 2022 |
| Title |
Foodomics study on the anti-proliferative activity mechanisms on HT-29 colon cancer cells in response to banana passion fruit (Passiflora mollissima) seeds PLE-extract |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
Passiflora mollissima commonly known as “banana passion fruit” is usually consumed as fresh food or processed products, being seeds and peel the main by-products of the industrial processing. The potentially bioactive metabolites from banana passion fruit PLE-extract seeds have been recently characterized by HPLC-HRMS after sequential pressurized liquid extraction (PLE)
To apply a Foodomics approach to study the effects of a banana passion fruit seeds PLE-extract (with high antioxidant capacity and enriched in phenolic-type compounds) on the transcriptome and metabolome of HT-29 colon cancer cells.
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| Overall design |
Transcriptome and metabolome analyses of HT-29 colon cancer cells untreated or treated with a banana passion fruit seeds PLE-extract for 48 hours. Three biological replicates were included in the experiment.
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| Contributor(s) |
Ballesteros-Vivas D, Alvarez-Rivera G, León C, Morantes SJ, Ibánez E, Parada-Alfonso F, Cifuentes A, Valdés A |
| Citation(s) |
32156385 |
| Submission date |
Jul 02, 2019 |
| Last update date |
May 25, 2022 |
| Contact name |
Alberto Valdés |
| E-mail(s) |
a.valdes@csic.es
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| Phone |
0034910017991
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| Organization name |
Instituto de Investigación en Ciencias de la Alimentación
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| Department |
Bioactividad y Análisis de Alimentos
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| Lab |
Foodomics
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| Street address |
C\Nicolás Cabrera, 9
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| City |
Madrid |
| State/province |
Madrid |
| ZIP/Postal code |
28049 |
| Country |
Spain |
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| Platforms (1) |
| GPL13607 |
Agilent-028004 SurePrint G3 Human GE 8x60K Microarray (Feature Number version) |
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| Samples (3) |
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| Relations |
| BioProject |
PRJNA552261 |
