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| Status |
Public on May 24, 2022 |
| Title |
Foodomics study on the anti-proliferative activity mechanisms on HT-29 colon cancer cells in response to golden berry (Physalis peruviana L.) calyx extracts |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
Different research works have described goldenberry calyx as a source of bioactive compounds, but limited information is available about its effects at the transcriptome and metabolome levels
To apply a Foodomics approach to study the effects of a goldenberry calyx PLE-extract on the transcriptome and metabolome of HT-29 colon cancer cells.
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| Overall design |
Transcriptome and metabolome analyses of HT-29 colon cancer cells untreated or treated with a goldenberry calyx PLE-extract for 48 hours. Three biological replicates were included in the experiment.
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| Contributor(s) |
Ballesteros-Vivas D, Alvarez-Rivera G, León C, Morantes SJ, Ibánez E, Parada-Alfonso F, Cifuentes A, Valdés A |
| Citation |
Diego Ballesteros-Vivas, Gerardo Alvarez-Rivera, Carlos León, Sandra Johanna Morantes, Elena Ibánez, Fabián Parada-Alfonso, Alejandro Cifuentes, and Alberto Valdés. Anti-proliferative bioactivity against HT-29 colon cancer cells of a withanolides-rich extract from golden berry (Physalis peruviana L.) calyx investigated by Foodomics. Journal of Functional Foods, Volume 63, 2019, 103567, doi:10.1016/j.jff.2019.103567
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| Submission date |
Jun 17, 2019 |
| Last update date |
May 26, 2022 |
| Contact name |
Alberto Valdés |
| E-mail(s) |
a.valdes@csic.es
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| Phone |
0034910017991
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| Organization name |
Instituto de Investigación en Ciencias de la Alimentación
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| Department |
Bioactividad y Análisis de Alimentos
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| Lab |
Foodomics
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| Street address |
C\Nicolás Cabrera, 9
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| City |
Madrid |
| State/province |
Madrid |
| ZIP/Postal code |
28049 |
| Country |
Spain |
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| Platforms (1) |
| GPL13607 |
Agilent-028004 SurePrint G3 Human GE 8x60K Microarray (Feature Number version) |
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| Samples (3) |
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| Relations |
| BioProject |
PRJNA549278 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE132855_RAW.tar |
67.7 Mb |
(http)(custom) |
TAR (of TXT) |
| Processed data included within Sample table |
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