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Series GSE132718 Query DataSets for GSE132718
Status Public on Jun 14, 2019
Title Comparison of RhoE and RhoEα regulated pathways
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary We identified a new RhoE isoform, RhoEα, and compared the differentially regulated signalings by these two proteins. Both RhoE and RhoEα were first knocked out via CRISPR/Cas9 in HEK 293 cells and HeLa cells (KO cells), followed by RhoE and RhoEα reintroduction (RhoE reintroduction cells and RhoEα reintroduction cells, resepectively). Wild-type cells, KO cells, RhoE reintrocution cells, and RhoEα reintroduction cells were then subjected to RNA-seq analysis.
Overall design Examination of genes individually regulated by RhoE and RhoEα
Contributor(s) Dai Y, Ma W, Wang J, Chang J
Citation(s) 33060740
Submission date Jun 13, 2019
Last update date Oct 27, 2020
Contact name Jiang Chang
Organization name Texas A&M University Institute of Biosciences and Technology
Department Center for Translational Cancer Research
Street address 2121 W. Holcombe Blvd.
City Houston
State/province TX
ZIP/Postal code 77030
Country USA
Platforms (1)
GPL24676 Illumina NovaSeq 6000 (Homo sapiens)
Samples (8)
GSM3890681 HEK 293 wild-type
GSM3890682 HEK 293 KO
GSM3890683 HEK 293 RhoE reintroduction
BioProject PRJNA548801
SRA SRP201386

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Supplementary file Size Download File type/resource
GSE132718_RAW.tar 6.6 Mb (http)(custom) TAR (of XLS)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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