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Series GSE132344 Query DataSets for GSE132344
Status Public on Mar 16, 2023
Title Epigenetic misactivation of a distal developmental enhancer drives SOX2 overexpression in multiple cancer subtypes
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Genome binding/occupancy profiling by high throughput sequencing
Summary We have investigated a distal regulatory region that drives SOX2 overexpression in multiple cancer subtypes
Overall design WT and homozygous enhancer-deleted (dEnh) cells were submitted for ribo-depelted total RNA-seq and ATAC-seq in three replicates each.
Web link
Contributor(s) Abatti LE, Mitchell JA
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Submission date Jun 06, 2019
Last update date Mar 19, 2023
Contact name Jennifer Mitchell
Phone 4169786711
Organization name University of Toronto
Department Cell and Systems Biology
Street address 25 Harbord Street
City Toronto
State/province Ontario
ZIP/Postal code M5S 3G5
Country Canada
Platforms (2)
GPL16791 Illumina HiSeq 2500 (Homo sapiens)
GPL24676 Illumina NovaSeq 6000 (Homo sapiens)
Samples (12)
GSM3860399 MCF7_WT_RNA_1
GSM3860400 MCF7_WT_RNA_2
GSM3860401 MCF7_WT_RNA_3
BioProject PRJNA547640
SRA SRP200701

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE132344_RAW.tar 2.4 Gb (http)(custom) TAR (of BEDGRAPH)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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