|
| Status |
Public on May 05, 2021 |
| Title |
RNA-seq analysis of HNSCC cells after JQ1 treatment |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We performed RNA sequencing (RNA-seq) of HNSCC cells to examine genome-wide gene expression pattern following JQ1 treatment. BET inhibition by JQ1 significantly inhibits a cohort of key oncogenes associate with tumorigenesis and metastasis. Suggesting BET inhibition is effective strategy to suppress the tumorigenesis and metastasis of head and neck squamous cell carcinoma.
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| |
|
| Overall design |
Examination of RNA-seq of HNSCC cells treated with JQ1.
|
| |
|
| Contributor(s) |
Li J |
| Citation(s) |
34172737 |
| Submission date |
May 30, 2019 |
| Last update date |
Jul 14, 2021 |
| Contact name |
Jiong Li |
| E-mail(s) |
jli29@vcu.edu
|
| Phone |
3105617186
|
| Organization name |
VCU
|
| Street address |
800 E Leigh Street, suite 212
|
| City |
Richmond |
| State/province |
Virginia |
| ZIP/Postal code |
23298 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL21290 |
Illumina HiSeq 3000 (Homo sapiens) |
|
| Samples (6)
|
|
| Relations |
| BioProject |
PRJNA545475 |
| SRA |
SRP199867 |
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