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Series GSE131967 Query DataSets for GSE131967
Status Public on May 05, 2021
Title RNA-seq analysis of HNSCC cells after JQ1 treatment
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary We performed RNA sequencing (RNA-seq) of HNSCC cells to examine genome-wide gene expression pattern following JQ1 treatment. BET inhibition by JQ1 significantly inhibits a cohort of key oncogenes associate with tumorigenesis and metastasis. Suggesting BET inhibition is effective strategy to suppress the tumorigenesis and metastasis of head and neck squamous cell carcinoma.
Overall design Examination of RNA-seq of HNSCC cells treated with JQ1.
Contributor(s) Li J
Citation(s) 34172737
Submission date May 30, 2019
Last update date Jul 14, 2021
Contact name Jiong Li
Phone 3105617186
Organization name VCU
Street address 800 E Leigh Street, suite 212
City Richmond
State/province Virginia
ZIP/Postal code 23298
Country USA
Platforms (1)
GPL21290 Illumina HiSeq 3000 (Homo sapiens)
Samples (6)
GSM3832902 SCC1_con
GSM3832903 SCC1_JQ1
GSM3832904 SCC22B_con
BioProject PRJNA545475
SRA SRP199867

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Supplementary file Size Download File type/resource
GSE131967_RAW.tar 1.5 Mb (http)(custom) TAR (of TXT)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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