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| Status |
Public on Dec 01, 2021 |
| Title |
TBC1D3 Associates with the Histone Lysine N-methyltransferase G9a to Affect the Promotion of Neural Progenitors and Cortical Expansion in an Epigenetic Way [RNA-Seq] |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
we conducted RNA sequencing using human cerebral organoids treated with TAT peptides
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| Overall design |
Human cerebral organoids were treated with TAT peptides for two groups, that is, TAT-Scrambled (Short for TAT-Scr) with the sequence of YGRKKRRQRRR-FRVRYWFQGCHSEDPWR and TAT-465-481, a special peoptide designed for inhibition of TBC1D3, with the sequence of YGRKKRRQRRR-EGPWFRHYDFRQSCWVR. After 4 days incubation, human cerebral organoid tissues were extracted at cultured day 16 and bulk RNA from TAT-Scr group or TAT-465-481 group was extracted to be sequenced.
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| Contributor(s) |
Hou Q, Luo Z |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
May 15, 2019 |
| Last update date |
Dec 01, 2021 |
| Contact name |
qiongqiong hou |
| E-mail(s) |
houqq@shanghaitech.edu.cn
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| Organization name |
shanghaitech university
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| Street address |
huanke road 199
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| City |
shanghai |
| ZIP/Postal code |
20000 |
| Country |
China |
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| Platforms (1) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
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| Samples (2) |
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| This SubSeries is part of SuperSeries: |
| GSE131254 |
TBC1D3 Associates with the Histone Lysine N-methyltransferase G9a to Affect the Promotion of Neural Progenitors and Cortical Expansion in an Epigenetic Way |
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| Relations |
| BioProject |
PRJNA543055 |
| SRA |
SRP198477 |
