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Series GSE130617 Query DataSets for GSE130617
Status Public on May 03, 2019
Title Whole genome bisulfite genome analysis of OX40L-Jagged-1 expanded Treg and Teff cells
Organism Mus musculus
Experiment type Methylation profiling by high throughput sequencing
Summary NOD mice were treated with PBS or OX40L and Jagged-1 proteins once a week for three weeks. A week after final treatment CD4+CD25- Teff cells and CD4+CD25hi Treg cells were sorted by FACS. Genomic DNA isolated from sorted cells and differences in DNA methylation pattern in these cell types between PBS and OX40L-Jagged-1 treated mice was analyzed by whole genome bi-sulfite sequencing.
Overall design Examination of methylation pattern in Teff vs Treg cells between PBS and OX40L-JAG1 mice.
Contributor(s) Kumar P, Maienschein-Cline M, Arbieva Z, Prabhakar B
Citation(s) 31704879
Submission date May 02, 2019
Last update date Nov 13, 2019
Contact name Prabhakaran Kumar
Phone 3122866678
Organization name UIC
Department Microbiology and Immunology
Street address 835 S Wolcott Ave.
City Chiciago
State/province Illinois
ZIP/Postal code 60612
Country USA
Platforms (1)
GPL24247 Illumina NovaSeq 6000 (Mus musculus)
Samples (4)
GSM3744922 Ctrl Teff
GSM3744923 Ctrl Treg
GSM3744924 OX40JAG Teff
BioProject PRJNA540788
SRA SRP194541

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Supplementary file Size Download File type/resource
GSE130617_cpg_quant.txt.gz 208.1 Mb (ftp)(http) TXT
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Raw data are available in SRA
Processed data are available on Series record

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