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Series GSE130457 Query DataSets for GSE130457
Status Public on Jan 04, 2021
Title Aberrant gene expression leakage from linage-specific heterochromatic loci during senescence
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Genome binding/occupancy profiling by high throughput sequencing
Summary To understand induction of cornification genes on lineage appropriate (keratinocyte differentiation) and inappropriate (fibroblast senescence) conditions , we generated histone modification and gene expression dataset. Then we compared these keratinocyte's dataset with our previous fibroblast senescence dataset in the study.
 
Overall design Histone modification and mRNA profiles of proliferating and differentiated keratinocytes were generated.
 
Contributor(s) Tomimatsu K, Bihary D, Samarajiwa SA, Narita M
Citation https://doi.org/10.21203/rs.3.rs-120562/v1
Submission date Apr 29, 2019
Last update date Jan 04, 2021
Contact name Shamith Samarajiwa
Organization name Imperial College London
Department Genetics and Genomics Section Department of Metabolism, Digestion and Reproduction
Lab Computational Biology & Data Science
Street address ICTEM Building, Hammersmith Campus, Du Cane Road,
City London
ZIP/Postal code W12 0NN
Country United Kingdom
 
Platforms (3)
GPL16791 Illumina HiSeq 2500 (Homo sapiens)
GPL18573 Illumina NextSeq 500 (Homo sapiens)
GPL20301 Illumina HiSeq 4000 (Homo sapiens)
Samples (34)
GSM3738970 H3K9me3_Growing_ChIP-seq [SLX-11527.A014]
GSM3738971 H3K9me3_Growing_ChIP-seq [SLX-11527.A015]
GSM3738972 H3K9me3_Differentiated_ChIP-seq [SLX-11527.A016]
Relations
BioProject PRJNA540290
SRA SRP194182

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE130457_RAW.tar 2.0 Gb (http)(custom) TAR (of BED, BW, NARROWPEAK, TXT)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file
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