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| Status |
Public on Aug 10, 2022 |
| Title |
Single-cell RNA-seq of mouse thymus iNKT cells |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Invariant natural killer T cells (iNKT) cells are innate-like T cells, selected from thymic cortex-resident CD4+CD8+ double positive (DP) thymocytes. Despite major advances in the understanding of iNKT cells development, the heterogeneity of iNKT subsets and underlying molecular programs that guide iNKT cell-lineage remain unclear.
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| Overall design |
We profiled the transcriptome patterns of individual mouse thymic iNKT cells across their developmental stages (stages 0 to 3) using a droplet-based single-cell RNA-sequencing (scRNA-seq) approach.
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| Contributor(s) |
Wang J, Adrianto I, Wu X, Zhou L, Mi Q |
| Citation(s) |
35915069, 37336875 |
| |
| Submission date |
Apr 23, 2019 |
| Last update date |
Jun 27, 2023 |
| Contact name |
Indra Adrianto |
| E-mail(s) |
iadrian1@hfhs.org
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| Phone |
313-874-5999
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| Organization name |
Henry Ford Health System
|
| Department |
Public Health Sciences
|
| Street address |
1 Ford Place
|
| City |
Detroit |
| State/province |
MI |
| ZIP/Postal code |
48202 |
| Country |
USA |
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| Platforms (1) |
| GPL21103 |
Illumina HiSeq 4000 (Mus musculus) |
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| Samples (8)
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| GSM3733520 |
NKT_mm_Thymus_St0_1: Mouse thymus stage 0 iNKT cell sample 1 |
| GSM3733521 |
NKT_mm_Thymus_St0_2: Mouse thymus stage 0 iNKT cell sample 2 |
| GSM3733522 |
NKT_mm_Thymus_St1_1: Mouse thymus stage 1 iNKT cell sample 1 |
| GSM3733523 |
NKT_mm_Thymus_St1_2: Mouse thymus stage 1 iNKT cell sample 2 |
| GSM3733524 |
NKT_mm_Thymus_St2_1: Mouse thymus stage 2 iNKT cell sample 1 |
| GSM3733525 |
NKT_mm_Thymus_St2_2: Mouse thymus stage 2 iNKT cell sample 2 |
| GSM3733526 |
NKT_mm_Thymus_St3_1: Mouse thymus stage 3 iNKT cell sample 1 |
| GSM3733527 |
NKT_mm_Thymus_St3_2: Mouse thymus stage 3 iNKT cell sample 2 |
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| Relations |
| BioProject |
PRJNA534242 |
| SRA |
SRP193459 |
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