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Series GSE130076 Query DataSets for GSE130076
Status Public on Dec 10, 2021
Title Single cell transcriptome analysis of distal adult human lung airway cells
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary To comprehensively study the heterogeneity within distal airway epithelium, we performed single cell transcriptomic analysis of the normal human donor lung samples. Our analysis reveals that secretory (club) and basal cells in the distal lung airway epithelial cells are highly heterogenous. Further interrogation of secretory cells identified a subpopulation with potential for alveolar differentiation in vitro, implicating distal lung airway secretory cells as new candidates in alveolar repair and regeneration.
Overall design Single cells were isolated via flow cytometry based on EPCAM and HTII-280 from an unidentified human donor lung tissue
Contributor(s) Kathiriya JJ, Chapman HA
Citation(s) 35355013
Submission date Apr 19, 2019
Last update date Apr 22, 2022
Contact name Jaymin J Kathiriya
Organization name University of California San Francisco
Department Medicine
Lab Chapman Lab
Street address 513 Parnassus Ave
City San Francisco
State/province CA
ZIP/Postal code 94131
Country USA
Platforms (1)
GPL24676 Illumina NovaSeq 6000 (Homo sapiens)
Samples (1)
GSM3731532 HT280neg_Single cell
BioProject PRJNA533797
SRA SRP193092

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Supplementary file Size Download File type/resource
GSE130076_RAW.tar 80.7 Mb (http)(custom) TAR (of MTX, TSV)
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Raw data are available in SRA
Processed data provided as supplementary file

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