|
| Status |
Public on Apr 12, 2020 |
| Title |
Genome-wide localization of RNA polymerase II and histone modifications in diffuse intrinsic pontine glioma cells in response to CDK9 inhibition |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
We report the application of chromatin immunoprecipitation for high-thoughput profiling of RNA polymerase II and histone modifications (H3K27me3 and H3K27ac) in diffuse intrinsic pontine glioma cells (DIPG) in response to CDK9 inhibition
|
| |
|
| Overall design |
Examination of the localization of RNA polymerase II and two different histone modifications in DIPG cells
|
| |
|
| Contributor(s) |
Dahl NA, Danis E, Vibhakar R |
| Citation(s) |
32268092 |
| Submission date |
Apr 14, 2019 |
| Last update date |
Aug 31, 2020 |
| Contact name |
Etienne Danis |
| E-mail(s) |
etienne.danis@cuanschutz.edu
|
| Organization name |
University of Colorado, Denver - Anschutz Medical Campus
|
| Street address |
12800 E. 19th Ave
|
| City |
Aurora |
| State/province |
CO |
| ZIP/Postal code |
80045 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
| Samples (10)
|
| GSM3721939 |
RNA_polymerase_II_ChIP-seq_atuveciclib_DIPG7 |
| GSM3721940 |
H3K27ac_ChIP-seq_DIPG7_without_WT_H3_3_overexpression_untreated |
| GSM3721941 |
H3K27ac_ChIP-seq_DIPG7_with_WT_H3_3_overexpression_untreated |
| GSM3721942 |
H3K27me3_ChIP-seq_DIPG7_without_WT_H3_3_overexpression_untreated |
| GSM3721943 |
H3K27me_ChIP-seq_DIPG7_with_WT_H3_3_overexpression_untreated |
| GSM3721944 |
Total_H3_ChIP-seq_DIPG7_without_WT_H3_3_overexpression_untreated |
| GSM3721945 |
Total_H3_ChIP-seq_DIPG7_with_WT_H3_3_overexpression_untreated |
|
| Relations |
| BioProject |
PRJNA532766 |
| SRA |
SRP192516 |
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