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Series GSE129563 Query DataSets for GSE129563
Status Public on Jul 30, 2019
Title Couple transcriptome and genomic data obtained from the PDXs to identify pathways linking oncogenic alterations
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary Purpose: Study the changes in cell transcriptome in breast cancer with respect to normal breast tissue in association with somatic mutations
Methods: RNA was extracted from frozen normal breast tissues and PDXs cells
Results: We found over-expression of oncogenic pathways associated with oncogenic mutations in PDXs
Overall design Analysis of differential gene expression in metastatic breast cancer PDXs
Contributor(s) Punzi S, Meliksetyan M, Riva L, Marocchi F, Pruneri G, Criscitiello C, Orsi F, Spaggiari L, Curigliano G, Pelicci PG, Lanfrancone L
Citation(s) 31216647
Submission date Apr 10, 2019
Last update date Jul 30, 2019
Contact name Marine Melixetian
Organization name European Institute of Oncology
Street address via Adamello 16
City Milano
ZIP/Postal code 20141
Country Italy
Platforms (1)
GPL24676 Illumina NovaSeq 6000 (Homo sapiens)
Samples (21)
GSM3716385 MBC26_Rep1
GSM3716386 MBC26_Rep2
GSM3716387 MBC26_Rep3
BioProject PRJNA531824
SRA SRP191759

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SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE129563_NP_MBC_HTcounts.norm.xlsx.gz 5.1 Mb (ftp)(http) XLSX
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Raw data are available in SRA
Processed data are available on Series record

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