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Series GSE127221 Query DataSets for GSE127221
Status Public on Mar 04, 2019
Title Expression profiling of PBMCs from VA-ECLS patients
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary We profiled RNA expression by means of single cell RNA-Seq from a total of ~60,000 cells from 38 patients undergoing VA-ECMO due to acute heart failure (including acute exacerbation of chronic failure). Samples were taken at the time of initiation of ECMO (mean +/- 79 minutes from cannulation).
Overall design Survival analysis, 30 day survival, with cross sectional analysis of gene expression at start of VA-ECLS
Submitters plan to submit raw files to dbGaP to protect patient sequence privacy
Contributor(s) Kort EJ, Jovinge S
Citation Eric J. Kort, Matthew Weiland, Edgars Grins, Emily Eugster, Hsiao-yun Milliron, Catherine Kelty, Nabin Manandhar Shrestha, Tomasz Timek, Marzia Leacche, Stephen J Fitch, Theodore J Boeve, Greg Marco, Michael Dickinson, Penny Wilton, Stefan Jovinge. Single cell transcriptomics identifies immunologic priming related to extra corporeal life support survival. bioRxiv 568659; doi:10.1101/568659
Submission date Feb 26, 2019
Last update date Mar 19, 2019
Contact name Eric Kort
Phone 6162345442
Organization name Van Andel Research Institute
Lab Jovinge Lab
Street address 333 Bostwick NE
City Grand Rapids
State/province MI
ZIP/Postal code 49503
Country USA
Platforms (1)
GPL24676 Illumina NovaSeq 6000 (Homo sapiens)
Samples (38)
GSM3631057 Patient 1
GSM3631058 Patient 2
GSM3631059 Patient 3
BioProject PRJNA524362

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE127221_PBMC_merged_filtered_recoded.rds.gz 170.2 Mb (ftp)(http) RDS
GSE127221_PBMC_merged_filtered_recoded.txt.gz 116.4 Mb (ftp)(http) TXT
GSE127221_metadata.rds.gz 1.7 Kb (ftp)(http) RDS
GSE127221_metadata.txt.gz 791 b (ftp)(http) TXT
Raw data not provided for this record
Processed data are available on Series record

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