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| Status |
Public on Jun 05, 2020 |
| Title |
Epigenetic homogeneity underlies sperm programming for embryonic transcription |
| Organisms |
Xenopus laevis; Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
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| Summary |
Epigenetic homogeneity underlies sperm programming for embryonic transcription
single-ended ChIP-Seq libraries from sperm, egg extract (-geminin) treated sperm, egg extract (+geminin) treated sperm, and St 7 embryos with antibody for H3Kme3, H3K27me3, 3 replicates for each histone modification pull-down
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| Overall design |
30 samples, paired-ended and single-ended ChIP-Seq libraries from sperm, egg extract (-geminin) treated sperm, egg extract (+geminin) treated sperm, and St 7 embryos with antibody for H3Kme3, H3K27me3, 3 replicates for each histone modification pull-down.
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*The authors state the following regarding the human raw data: "We don't have the required patient consents to deposit them". Thus, this submission is incomplete.
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| Contributor(s) |
Oikawa M, Simeone A, Hormanseder E, Teperek M, D’Santos C, Bradshaw CR, O’Doherthy A, Freour T, David L, Grzybowski AT, Ruthenburg AJ, Gurdon J, Jullien J |
| Citation(s) |
32661239 |
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| Submission date |
Jan 31, 2019 |
| Last update date |
Jul 27, 2020 |
| Contact name |
Angela Simeone |
| E-mail(s) |
angela.simeone@gmail.com
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| Organization name |
University of Cambridge
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| Department |
Cancer Research UK Cambridge Institute
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| Street address |
Robinson Way
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| City |
Cambridge |
| ZIP/Postal code |
CB2 0RE |
| Country |
United Kingdom |
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| Platforms (2) |
| GPL18460 |
Illumina HiSeq 1500 (Homo sapiens) |
| GPL21046 |
Illumina HiSeq 1500 (Xenopus laevis) |
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| Samples (36)
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| Relations |
| BioProject |
PRJNA518148 |
| SRA |
SRP183098 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE125982_H3K27me3_sperm_EggTr_2rep_strict.bed.gz |
461.2 Kb |
(ftp)(http) |
BED |
| GSE125982_H3K27me3_sperm_EggTr_GMN_2rep_strict.bed.gz |
182.7 Kb |
(ftp)(http) |
BED |
| GSE125982_H3K4me3_sperm_EggTr_2rep_strict.bed.gz |
664.2 Kb |
(ftp)(http) |
BED |
| GSE125982_H3K4me3_sperm_EggTr_GMN_2rep_strict.bed.gz |
552.1 Kb |
(ftp)(http) |
BED |
| GSE125982_HMD_macs2_nodup_190_H3K27me3_common_rep1_rep2.broadPeak.coverage.bed.gz |
640.3 Kb |
(ftp)(http) |
BED |
| GSE125982_HMD_macs2_nodup_190_H3K4me3_common_rep1_rep2.narrowPeak.coverage.bed.gz |
420.0 Kb |
(ftp)(http) |
BED |
| GSE125982_macs2_nodup_190_Alan3_H3K27me3_narrowpeaks.HMD.bed.gz |
1.3 Mb |
(ftp)(http) |
BED |
| GSE125982_macs2_nodup_190_Alan3_H3K4me3_narrowpeaks.HMD.bed.gz |
645.7 Kb |
(ftp)(http) |
BED |
| GSE125982_macs2_nodup_190_H3K27me3_broad_common_rep1_rep2.broadPeak.gz |
1.3 Mb |
(ftp)(http) |
BROADPEAK |
| GSE125982_macs2_nodup_190_H3K4me3_common_rep1_rep2.narrowPeak.gz |
885.3 Kb |
(ftp)(http) |
NARROWPEAK |
| GSE125982_macs2_st7_Ind15_19_H3K4me3_rep1_peaks.narrowPeak.gz |
328.8 Kb |
(ftp)(http) |
NARROWPEAK |
| GSE125982_macs2_st7_Ind18_12_H3K4me3_rep2_peaks.narrowPeak.gz |
534.4 Kb |
(ftp)(http) |
NARROWPEAK |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data are available on Series record |
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