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Series GSE125858 Query DataSets for GSE125858
Status Public on Jun 13, 2019
Title Single-cell transcriptomic analysis of tissue resident memory T cells in human lung cancer [ATAC-Seq]
Organism Homo sapiens
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary High numbers of tissue-resident memory T (TRM) cells have been associated with better clinical outcomes in cancer patients. However, the molecular characteristics that drive their efficient immune response to tumors are poorly understood. Here, using single-cell and bulk transcriptomic analysis of purified populations of TRM and non-TRM cells we characterise these populations
Overall design Population and single cell profiling of subtypes of CD8 cells isolated from human lung and lung tumour samples with flow cytometry
Contributor(s) Clarke J, Panwar B, Madrigal A, Singh D, Wood O, Chee S, Awad A, King E, Woo E, Alzetani A, Seumois G, Thomas G, Ganesan A, Friedmann P, Sanchez-Elsner T, Ay F, Ottensmeier C, Vijayanand P
Citation(s) 31227543, 36701231
Submission date Jan 29, 2019
Last update date Aug 08, 2023
Contact name Pandurangan Vijayanand
Organization name La Jolla Institute for Allergy and Immunology
Department Division of Vaccine Discovery
Lab VD-Vijay
Street address 9420 Athena Circle
City La Jolla
State/province California
ZIP/Postal code 92037
Country USA
Platforms (2)
GPL16791 Illumina HiSeq 2500 (Homo sapiens)
GPL24676 Illumina NovaSeq 6000 (Homo sapiens)
Samples (9)
GSM3583356 Pool1A_TIM3Pos_IL7Rneg_TRM
GSM3583357 Pool1B_TIM3Pos_IL7Rneg_TRM
GSM3583358 Pool2A_Non_TRM
This SubSeries is part of SuperSeries:
GSE111898 Single-cell transcriptomic analysis of tissue resident memory T cells in human lung cancer.
BioProject PRJNA517712
SRA SRP182843

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Supplementary file Size Download File type/resource 213.1 Mb (ftp)(http) BW 204.3 Mb (ftp)(http) BW
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