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Series GSE125662 Query DataSets for GSE125662
Status Public on Apr 01, 2019
Title RNA-seq data of alveolar type 2 epithelial cell derived from organoids treated with IL-1b or TNFa
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary Treatment with IL-1b or TNFa enhance the proliferation of alveolar type 2 cells in organoid culture. Here, we examine the downstream mechanisms that enhance AEC2 proliferation after IL-1b and TNFa treatments, we performed RNA-seq analysis of AEC2s isolated from organoids 6 hrs after exposure to either cytokine. We identified 165 differentially expressed genes that were common in both IL-1b and TNFa treated AEC2s compared to saline treated controls.
Overall design mRNA was isolated from FACS-sorted cells and sequenced using Illumina HiSeq X
Contributor(s) Katsura H, Kobayashi Y, Rao Tata P, Hogan BL
Citation(s) 30930244
Submission date Jan 25, 2019
Last update date Apr 23, 2019
Contact name Hiroaki Katsura
Organization name Duke University
Street address 353 Nanaline Duke Bldg
City Durham
State/province NC
ZIP/Postal code 27710
Country USA
Platforms (1)
GPL21273 HiSeq X Ten (Mus musculus)
Samples (9)
GSM3579739 Control #1
GSM3579740 Control #2
GSM3579741 Control #3
BioProject PRJNA517119
SRA SRP182054

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Supplementary file Size Download File type/resource
GSE125662_count_data.csv.gz 370.0 Kb (ftp)(http) CSV
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Raw data are available in SRA
Processed data are available on Series record

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