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Series GSE124625 Query DataSets for GSE124625
Status Public on Jan 04, 2019
Title RNA sequencing results of L1-FGGY+/- lung squamous cell carcinoma tumor samples
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary In order to explore pathways which were affected by L1-FGGY in lung squamous cell carcinoma (LUSC), we performed RNA sequencing on L1-FGGY+/- LUSC tumor samples. We identified 1529 (826 up and 703 down) dysregulated genes in L1-FGGY positive tissues with an adjusted p value less than 0.05. The KEGG enrichment analysis indicated that many signaling pathways were upregulated in L1-FGGY positive tissues, including glutathione metabolism, metabolism of xenobiotics by cytochrome P450, arachidonic acid metabolism, metabolic pathways, and glycerolipid metabolism, most of which were metabolic pathways, especially in lipid-related metabolism.
Overall design RNA sequencing profiles of L1-FGGY+/- LUSC tumor samples were generated by deep sequencing, in triplicate, using Illumina NovaSeq, followed by differential expression analysis and KEGG enrichment analysis.
Contributor(s) Zhang R, Sun Z
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Submission date Jan 03, 2019
Last update date Apr 20, 2022
Contact name Zeguo Sun
Phone 6466427380
Organization name Ichan School of Medicine at Mount Sinai
Street address 1468 Madison Avenue
City New York
ZIP/Postal code 10029
Country USA
Platforms (1)
GPL24676 Illumina NovaSeq 6000 (Homo sapiens)
Samples (19)
GSM3538094 H_1_136
GSM3538095 H_2_255
GSM3538096 H_3_188
BioProject PRJNA512867
SRA SRP175171

Download family Format
SOFT formatted family file(s) SOFTHelp
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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE124625_RAW.tar 3.7 Mb (http)(custom) TAR (of TXT)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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