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Series GSE124551 Query DataSets for GSE124551
Status Public on Jan 03, 2019
Title Next Generation Sequencing Facilitates Quantitative Analysis of Peritoneal Macrophage Transcriptomes
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary Purpose:The purpose of this study is to detect activated or silenced genes during KAT8-deficient peritoneal macrophages and the control cells. Gene expression differences between two samples could be found using transcriptome profiling (RNA-seq) analysis.
Methods:Mouse peritoenal macrophages were harvested from mice 3 days after thioglycollate (Merck) injection. Macrophages RNA profiles were generated by deep sequencing,using Illumina.
Results: We mapped about 10 million sequence reads per sample to the mouse genome, identified hundreds of genes with significant mRNA variation between KAT8-deficient macrophages and the control cells.
 
Overall design Peritoneal macrophage mRNA profiles of KAT8fl/flLyz2-cre- and KAT8fl/flLyz2-cre+ mice were generated by deep sequencing.
 
Contributor(s) Wanwan H, Xingguang L
Citation missing Has this study been published? Please login to update or notify GEO.
Submission date Jan 02, 2019
Last update date Mar 01, 2019
Contact name Wanwan Huai
E-mail(s) master.girl@163.com
Phone +86 13817894471
Organization name zhejiang university
Street address yuhangtang road
City hangzhou
State/province -
ZIP/Postal code 310058
Country China
 
Platforms (1)
GPL21273 HiSeq X Ten (Mus musculus)
Samples (2)
GSM3536386 WT
GSM3536387 KAT8-KO
Relations
BioProject PRJNA512475
SRA SRP175007

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE124551_RAW.tar 300.0 Kb (http)(custom) TAR (of TXT)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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