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Series GSE123496 Query DataSets for GSE123496
Status Public on Apr 29, 2019
Title Human brain tissues from healthy controls and multiple sclerosis patients
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary Multiple sclerosis (MS) is characterized by cell proliferation, migration and damage in various cell types in different CNS regions and causes disabilities related to distinct neurological pathways, such as walking, vision and cognition. Here, region-specific transcriptomic approach was used to determine changes in gene expression in five different CNS regions (hippocampus, frontal cortex, internal capsule, corpus callosum, and parietal cortex) in MS.
Overall design Five MS patients (average age = 57.6 years) and five age-matched healthy controls (average age = 56.2 years) fresh frozen autopsy samples were obtained from Human Brain and Spinal Fluid Research Center in Los Angeles.
Contributor(s) Itoh Y, Voskuhl RR
Citation(s) 31040210
Submission date Dec 07, 2018
Last update date Jul 29, 2019
Contact name Yuichiro Itoh
Phone 3102068999
Organization name UCLA
Department Neurology
Street address 635 Charles E. Young Drive South
City Los Angeles
State/province California
ZIP/Postal code 90095
Country USA
Platforms (1)
GPL21290 Illumina HiSeq 3000 (Homo sapiens)
Samples (50)
GSM3505486 MS31CC
GSM3505487 MS32CF
GSM3505488 MS33Cp
BioProject PRJNA508944
SRA SRP173190

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE123496_Human_MSNL_counts.csv.gz 2.7 Mb (ftp)(http) CSV
GSE123496_Human_MSNL_counts.m.csv.gz 2.7 Mb (ftp)(http) CSV
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