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Series GSE122701 Query DataSets for GSE122701
Status Public on May 20, 2019
Title Transcriptome analysis of small molecule-mediated astrocyte-to-neuron reprogramming
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary Human astrocytes can be efficiently reprogrammed into functional neurons in culture by the addition of four small molecules. RNA-seq was performed to assess transcriptome alterations at different time points to characterize the molecular mechanisms.
Overall design RNA profiles of small molecule-treated human astrocyte culture at 6 time points throughout reprogramming, 3 replicates each.
Contributor(s) Ma N, Yin J, Chen G
Citation(s) 31231645
Submission date Nov 19, 2018
Last update date Aug 19, 2019
Contact name Gong Chen
Organization name Penn State University
Street address Old Main
City University Park
State/province PA
ZIP/Postal code 16802
Country USA
Platforms (1)
GPL21290 Illumina HiSeq 3000 (Homo sapiens)
Samples (18)
GSM3478713 human astrocyte, rep 1
GSM3478714 human astrocyte, rep 2
GSM3478715 human astrocyte, rep 3
BioProject PRJNA506035
SRA SRP169589

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Supplementary file Size Download File type/resource
GSE122701_counts.txt.gz 2.6 Mb (ftp)(http) TXT
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Raw data are available in SRA
Processed data are available on Series record

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