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Series GSE122556 Query DataSets for GSE122556
Status Public on Nov 01, 2023
Title RNA-sequencing (RNA-seq) analysis of gene expression of ASCs primed by LPS or dsDNA
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary In the inflammatory microenvironment, cytokines and products of pathogens could modulate the phenotype and activity of adipose tissue-derived mesenchymal stem cellsĀ (ASCs). So far, the gene expression profiles in lipopolysaccharide (LPS)- or double stranded DNA (dsDNA) -primed ASCs have less been extrapolated. We approached RNA-sequencing (RNA-seq) analysis and found that both LPS and dsDNA treatment markedly influence transcriptome regarding cytokine, chemotaxis/inflammatory genes and pattern recognition receptor (PRR) .
 
Overall design Different gene expression of ASCs primed by LPS or dsDNA
 
Contributor(s) Di C, Jiang Y
Citation missing Has this study been published? Please login to update or notify GEO.
Submission date Nov 15, 2018
Last update date Nov 01, 2023
Contact name jieming Qu
E-mail(s) jmqu0906@163.com
Organization name ruijin hospital
Street address Ruijin 2 road
City shanghai
ZIP/Postal code 200025
Country China
 
Platforms (1)
GPL21273 HiSeq X Ten (Mus musculus)
Samples (8)
GSM3473875 N1
GSM3473876 N2
GSM3473877 LPS1
Relations
BioProject PRJNA505608
SRA SRP168734

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE122556_All.HTSeq.counts.txt.gz 328.0 Kb (ftp)(http) TXT
GSE122556_LPSVSN.log2FC1.FDR0.05.txt.gz 41.3 Kb (ftp)(http) TXT
GSE122556_dsDNAVSLIPO.log2FC1.FDR0.05.txt.gz 79.8 Kb (ftp)(http) TXT
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Raw data are available in SRA
Processed data are available on Series record

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