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Series GSE120464 Query DataSets for GSE120464
Status Public on Sep 26, 2018
Title The  Tissue-Engineered Human Psoriatic Skin Substitute: A Valuable In Vitro Model to Identify Genes with Altered Expression in Lesional Psoriasis
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Psoriasis is a chronic inflammatory skin disease for which no cure has emerged. Its complex etiology requires the development of an in vitro model representative of the pathology.
Various skin substitutes were produced by tissue-engineering using biopsies from normal, healthy donors, or from lesional or non-lesional skin samples from patients with psoriasis, and their gene expression profiles were examined by DNA microarray.
Overall design Total RNA was isolated from five different healthy (18-, 22-, 23-, 38-, and 46-year old) and eight different psoriatic reconstructed skin substitutes (four lesional and four non-lesional (47-, 49-, 64-, and 70-year old))
Contributor(s) Pouliot R, Guérin SL, Soucy J, Benhassine M, Simard M, Pouliot-Bérubé C, Rioux G
Citation(s) 35625817
Submission date Sep 25, 2018
Last update date Jun 01, 2022
Contact name Roxane Pouliot
Phone 418-656-2131 7042
Organization name Centre de recherche en organogenese expérimentale de l'Université Laval/LOEX
Street address 1401, 18ème rue, aile R
City Québec
State/province Québec
ZIP/Postal code G1J 1Z4
Country Canada
Platforms (1)
GPL13607 Agilent-028004 SurePrint G3 Human GE 8x60K Microarray (Feature Number version)
Samples (13)
GSM3401100 Healthy_Skin substitute_F18
GSM3401101 Healthy_Skin substitute_F22
GSM3401102 Healthy_Skin substitute_F23
BioProject PRJNA493098

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE120464_RAW.tar 163.9 Mb (http)(custom) TAR (of TXT)
GSE120464_processed_data.txt.gz 2.0 Mb (ftp)(http) TXT
Processed data included within Sample table
Processed data are available on Series record

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