 |
 |
GEO help: Mouse over screen elements for information. |
|
| Status |
Public on Sep 26, 2018 |
| Title |
The Tissue-Engineered Human Psoriatic Skin Substitute: A Valuable In Vitro Model to Identify Genes with Altered Expression in Lesional Psoriasis |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Psoriasis is a chronic inflammatory skin disease for which no cure has emerged. Its complex etiology requires the development of an in vitro model representative of the pathology.
Various skin substitutes were produced by tissue-engineering using biopsies from normal, healthy donors, or from lesional or non-lesional skin samples from patients with psoriasis, and their gene expression profiles were examined by DNA microarray.
|
| |
|
| Overall design |
Total RNA was isolated from five different healthy (18-, 22-, 23-, 38-, and 46-year old) and eight different psoriatic reconstructed skin substitutes (four lesional and four non-lesional (47-, 49-, 64-, and 70-year old))
|
| |
|
| Contributor(s) |
Pouliot R, Guérin SL, Soucy J, Benhassine M, Simard M, Pouliot-Bérubé C, Rioux G |
| Citation(s) |
35625817 |
| Submission date |
Sep 25, 2018 |
| Last update date |
Jun 01, 2022 |
| Contact name |
Roxane Pouliot |
| E-mail(s) |
roxane.pouliot@pha.ulaval.ca
|
| Phone |
418-656-2131 7042
|
| Organization name |
Centre de recherche en organogenese expérimentale de l'Université Laval/LOEX
|
| Street address |
1401, 18ème rue, aile R
|
| City |
Québec |
| State/province |
Québec |
| ZIP/Postal code |
G1J 1Z4 |
| Country |
Canada |
| |
|
| Platforms (1) |
| GPL13607 |
Agilent-028004 SurePrint G3 Human GE 8x60K Microarray (Feature Number version) |
|
| Samples (13)
|
|
| Relations |
| BioProject |
PRJNA493098 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE120464_RAW.tar |
163.9 Mb |
(http)(custom) |
TAR (of TXT) |
| GSE120464_processed_data.txt.gz |
2.0 Mb |
(ftp)(http) |
TXT |
| Processed data included within Sample table |
| Processed data are available on Series record |
|
|
|
|
 |
Less...
More...