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Series GSE120173 Query DataSets for GSE120173
Status Public on Sep 20, 2018
Title Characterization of ST2+ and ST2- mTh cells in helminth infection
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary CD4+T cells are differentiated into Th1, Th2, Th17 and Treg cells after Antigen presentation by other cell types such as dendritic cells, macrophages and B cells in Lymph nodes. Those differentiated CD4+T cells are subdivided into cell subsets by their producing cytokines and surface markers. We recently identified that ST2 expressing Th2 cells highly produced IL-5 comparing to ST2- Th2 cells in helminth infection. In this study, we investigated the RNAseq analysis to characterize these Th2 cells.
Overall design Characterization of ST2+ and ST2- mTh cells are assessed by RNA-seq.
Contributor(s) Obata-Ninomiya K, Onodera A, Kato M, Nakayama T
Citation(s) 30275296
Submission date Sep 19, 2018
Last update date Dec 20, 2018
Contact name Atsushi Onodera
Organization name Chiba University
Department Immunology
Street address Chuo-ku Inohana 1-8-1
City Chiba
ZIP/Postal code 260-8670
Country Japan
Platforms (1)
GPL18480 Illumina HiSeq 1500 (Mus musculus)
Samples (12)
GSM3395235 N1_Nb_ST2hi_rep1
GSM3395236 N2_Nb_ST2lo_rep1
GSM3395237 N5_Nb_Naive_CD4_rep1
BioProject PRJNA491848
SRA SRP162113

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE120173_RAW.tar 1.8 Mb (http)(custom) TAR (of TXT)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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