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| Status |
Public on Nov 30, 2008 |
| Title |
Transcriptional profiles of Ad-F7 transduced macrophages treated with anti-IFNAR2 antibody or control isotype (IgG) |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Determine the role of interferons in the transcriptional profile of Ad-F7 transduced primary human macrophages using neutralizing antibody for the type I IFN receptor (IFNAR2).
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| |
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| Overall design |
Primary human macrophage preparations were transduced with Ad-GFP or Ad-F7 and treated with control isotype (IgG) or neutralizing antibody for the type I IFN receptor (IFNAR2). RNA was collected 24 hours later and subjected to microarray analysis. Data represents the average of 5 donors.
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| |
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| Contributor(s) |
Hernandez E, Goubau D, Hiscott J |
| Citation(s) |
19152337 |
| Submission date |
Jul 03, 2008 |
| Last update date |
Mar 20, 2017 |
| Contact name |
Eduardo Hernandez |
| E-mail(s) |
camacho99@yahoo.com
|
| Organization name |
Lady Davis Institute for Medical Research (JGH)
|
| Department |
Molecular Oncology Group
|
| Lab |
526
|
| Street address |
3755 Cote-Sainte-Catherine Road
|
| City |
Montreal |
| State/province |
Quebec |
| ZIP/Postal code |
H3T-1E2 |
| Country |
Canada |
| |
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| Platforms (1) |
| GPL6883 |
Illumina HumanRef-8 v3.0 expression beadchip |
|
| Samples (4)
|
| GSM303492 |
Ad-GFP transduction + IgG treatment in primary human macrophages (control Experiment 2) |
| GSM303494 |
Ad-F7 transduction + IgG treatment in primary human macrophages (Experiment 2) |
| GSM303496 |
Ad-GFP transduction + anti-IFNAR2 treatment in primary human macrophages (Experiment 2) |
| GSM303498 |
Ad-F7 transduction + anti-IFNAR2 treatment in primary human macrophages (Experiment 2) |
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| This SubSeries is part of SuperSeries: |
| GSE12120 |
Transcriptional re-programming of primary human macrophages by IRF-3 and IRF-7 |
|
| Relations |
| BioProject |
PRJNA114297 |
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