GEO Logo
   NCBI > GEO > Accession DisplayHelp Not logged in | LoginHelp
GEO help: Mouse over screen elements for information.
Series GSE118923 Query DataSets for GSE118923
Status Public on Oct 01, 2018
Title ATO treatment on mesenchymal stem cells (MSCs) interacting breast cancer cells
Organisms Homo sapiens; Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary Based on next generation RNA-seq, we examed Arsenic trioxide treatment (ATO) effect on MSCs-interacting MCF7 cells in 3D cultures. We found gap junction protein Cx43 is dramatically downregulated after ATO treatment..
Overall design human breast cancer cell line MCF-7 cells cocultured with mouse MSCs in 3D culture, with or without ATO treatment, are subject to NGS and then analyzed.
Contributor(s) Xiang Z, Hai W
Citation(s) 30423299
Submission date Aug 22, 2018
Last update date Feb 27, 2019
Contact name Hai Wang
Organization name Roswell Park Cancer Institute
Department Molecular and Cellular Biology
Lab Hai Wang
Street address Elm and Carlton Streets, MRC 328
City Buffalo
State/province NY
ZIP/Postal code 14263
Country USA
Platforms (1)
GPL19415 Illumina NextSeq 500 (Homo sapiens; Mus musculus)
Samples (6)
GSM3351301 Co_veh_rep1
GSM3351302 Co_veh_rep2
GSM3351303 Co_veh_rep3
BioProject PRJNA487341
SRA SRP158607

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE118923_CoAs.RData.gz 1.6 Mb (ftp)(http) RDATA
GSE118923_CoAs.csv.gz 1.2 Mb (ftp)(http) CSV
SRA Run SelectorHelp
Raw data are available in SRA
Processed data are available on Series record

| NLM | NIH | GEO Help | Disclaimer | Accessibility |
NCBI Home NCBI Search NCBI SiteMap