|
| Status |
Public on Sep 01, 2018 |
| Title |
scRNAseq reveals mechanisms of Merkel cell carcinoma acquired immunotherapy resistance [2] |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
PBMC and tumor specimen from a Merkel cell carcinoma tumor at time of immunotherapy resistance
|
| |
|
| Overall design |
PBMC and tumor specimen from a human patient with MCPyV associated Merkel cell carcinoma treated with T cell therapy and avelumab (anti-PD-L1), from a time point of late immunotherapy resistance; validation patient
|
| |
|
| Contributor(s) |
Paulson K, Chapuis A |
| Citation(s) |
30250229 |
| NIH grant(s) |
| Grant ID |
Grant title |
Affiliation |
Name |
| T32 CA009515 |
TRAINING IN CANCER BIOLOGY AND TRANSPLANTATION |
UNIVERSITY OF WASHINGTON |
NANCY ELLEN DAVIDSON |
| K08 CA169485 |
Targeting Leukemia with Memory CD8+ T cells Transduced to Express High-Affinity W |
FRED HUTCHINSON CANCER RESEARCH CENTER |
Aude Chapuis |
| K24 CA139052 |
Pathogenetic and prognostic studies for improved therapy of Merkel cell carcinoma |
UNIVERSITY OF WASHINGTON |
PAUL NGHIEM |
| R01 CA176841 |
Viral oncoprotein targeted immune therapy for Merkel cell carcinoma |
UNIVERSITY OF WASHINGTON |
PAUL NGHIEM |
| P30 CA015704 |
Cancer Center Support Grant |
FRED HUTCHINSON CANCER RESEARCH CENTER |
D GARY GILLILAND |
|
| Submission date |
Aug 02, 2018 |
| Last update date |
Nov 05, 2018 |
| Contact name |
Kelly Garneski Paulson |
| Organization name |
Fred Hutchinson Cancer Research Center
|
| Lab |
Chapuis Lab, Thomas D3-235
|
| Street address |
1100 Fairview Ave N
|
| City |
Seattle |
| State/province |
WA |
| ZIP/Postal code |
98109 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
| Samples (4)
|
|
| Relations |
| BioProject |
PRJNA484204 |
| SRA |
SRP157915 |
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