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Series GSE117671 Query DataSets for GSE117671
Status Public on Aug 03, 2018
Title Human proteins bound to RNA/DNA hybrid
Organism Homo sapiens
Experiment type Other
Summary RNA/DNA hybrids form when RNA hybridizes with its template DNA generating a three-stranded structure known as the R-loop. Knowledge of how they form and resolve, and their functional roles are limited. Here, we identified proteins that bind to RNA/DNA hybrids.
Overall design We identified transcripts bound by SRSF1 using two independent methods PAR-CLIP and RNA-IP. Then we characterized R-loop regions in human cells using DRIP-seq with the S9.6 antibody.
Contributor(s) Wang IX, Cheung VG, Hafner M, Zhu Z
Citation(s) 30108179
Submission date Jul 25, 2018
Last update date Sep 20, 2019
Contact name Zhengwei Zhu
Organization name University of Michigan
Street address 210 Washtenaw Ave
City Ann Arbor
ZIP/Postal code 48109
Country USA
Platforms (2)
GPL16791 Illumina HiSeq 2500 (Homo sapiens)
GPL21290 Illumina HiSeq 3000 (Homo sapiens)
Samples (5)
GSM3306019 SRSF1_PARClip-Bcell
GSM3306020 RIP-antiSRSF1-Bcell
GSM3306021 DRIP-S9.6-Bcell
BioProject PRJNA482858
SRA SRP155244

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Supplementary file Size Download File type/resource
GSE117671_RAW.tar 16.8 Mb (http)(custom) TAR (of XLSX)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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