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Series GSE116879 Query DataSets for GSE116879
Status Public on Jul 09, 2019
Title Response of triple negative breast cancer to BAZ2A/B inhibition and BET bromodomain inhibition alone and in combination (ChIPseq)
Organism Homo sapiens
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary Three triple negative breast cancer cell lines (MDAMB231, SUM159, and HCC1806) were treated with small molecule inhibitors (JQ1, BET bromodomain inhibitor; GSK2801, BAZ2A/B bromodomain inhibitor) or BAZ siRNA alone and in combination with JQ1 for 48 hours
 
Overall design 34 experimental samples analyzed, 2 chromatin input control samples
 
Contributor(s) Johnson GL, Bevill SM
Citation(s) 31000582
Submission date Jul 10, 2018
Last update date Oct 08, 2019
Contact name Gary L Johnson
E-mail(s) glj@med.unc.edu
Phone 919-843-3107
Organization name UNC Chapel Hill SOM
Department Pharmacology
Lab Gary L. Johnson
Street address 120 Mason Farm Road Genetic Medicine Building CB#7365
City Chapel Hill
State/province North Carolina
ZIP/Postal code 27599
Country USA
 
Platforms (1)
GPL18573 Illumina NextSeq 500 (Homo sapiens)
Samples (36)
GSM3263316 MDAMB231_BRD2_DMSO_48h
GSM3263317 MDAMB231_BRD2_10uMGSK2801_48h
GSM3263318 MDAMB231_BRD2_100nMJQ1_48h
This SubSeries is part of SuperSeries:
GSE116919 Response of triple negative breast cancer to BAZ2A/B inhibition and BET bromodomain inhibition alone and in combination
Relations
BioProject PRJNA480525
SRA SRP152992

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SOFT formatted family file(s) SOFTHelp
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Supplementary file Size Download File type/resource
GSE116879_HCC1806_BRD2_BAZ_siRNA_and_JQ1_peakclassification.xlsx 5.1 Mb (ftp)(http) XLSX
GSE116879_MDAMB231_BRD2_BAZ_siRNA_and_JQ1_peakclassification.xlsx 5.3 Mb (ftp)(http) XLSX
GSE116879_MDAMB231_BRD2_drug_treatment_peakclassification.xlsx 4.6 Mb (ftp)(http) XLSX
GSE116879_MDAMB231_BRD4_drug_treatment_peakclassification.xlsx 6.2 Mb (ftp)(http) XLSX
GSE116879_MDAMB231_BRD9_drug_treatment_peakclassification.xlsx 5.8 Mb (ftp)(http) XLSX
GSE116879_MDAMB231_rDNA_250bp_bins.xlsx 22.9 Kb (ftp)(http) XLSX
GSE116879_RAW.tar 42.7 Mb (http)(custom) TAR (of BED, NARROWPEAK)
GSE116879_SUM159_BRD2_drug_treatment_peakclassification.xlsx 6.2 Mb (ftp)(http) XLSX
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Raw data are available in SRA
Processed data provided as supplementary file
Processed data are available on Series record
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