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Series GSE116200 Query DataSets for GSE116200
Status Public on Jun 25, 2021
Title Bag3-P209L RNA Seq Project
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary Cardiac-specific Bag3-P209L transgenic (Tg+) mice develop dilated cardiomyopathy by 12 months of age. The goals of this project are to utilize RNA-sequencing to compare both cardiomyocyte and cardiac fibroblast transcriptomes between aged Bag3-P209L Tg+ and Bag3-WT mice to identify cardiomyocyte and fibroblast specific gene sets that contribute to the functional and morphological changes previously identified in Bag3-P209L Tg+ hearts.
Overall design Both cardiomyocytes and fibroblasts were isolated from three 16-month old Bag3-P209L Tg+ and three age matched Bag3-WT mice. RNA from cardiomyocytes and fibroblasts were then extracted and submitted to Novogene for cDNA library creation and subsequent RNA sequencing.
Contributor(s) Willis MS, Eaton SC
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Submission date Jun 25, 2018
Last update date Jun 25, 2021
Contact name Monte S Willis
Phone (317) 278-2674
Organization name University of Indiana School of Medicine
Street address 635 Barnhill Street Drive
City Indianapolis
ZIP/Postal code IN 46202
Country USA
Platforms (1)
GPL24247 Illumina NovaSeq 6000 (Mus musculus)
Samples (18)
GSM3213871 C36 F10 Tg+ rep1 Cardiomyocyte
GSM3213872 C36 F10 Tg+ rep2 Cardiomyocyte
GSM3213873 C36 F03 WT rep1 Cardiomyocyte
BioProject PRJNA477769
SRA SRP151238

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Supplementary file Size Download File type/resource
GSE116200_NormalizedCounts.tsv.gz 2.2 Mb (ftp)(http) TSV
GSE116200_RawCounts.tsv.gz 1.5 Mb (ftp)(http) TSV
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Raw data are available in SRA
Processed data are available on Series record

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