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| Status |
Public on Aug 01, 2018 |
| Title |
RNA-seq profiling of patient-derived xenograft models in Urothelial Cancer |
| Organisms |
Homo sapiens; Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
To probe the tissue source (cancer cell VS stromal cell) of gene expression in the mixed tumor samples, we took advantage of a set of Urothelial Cancer patient-derived xenograft (PDX) models given that the transcriptome in these models is a mixture of human RNA (derived from cancer cells) and mouse RNA (derived from stromal cells).
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| |
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| Overall design |
The cohort includes 5 different patient-derived PDX models, 3 replicates for each model, and thus a total of 15 samples
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| |
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| Contributor(s) |
Domingo-Domenech J, Wang L |
| Citation(s) |
30158554 |
| |
| Submission date |
Jun 22, 2018 |
| Last update date |
Nov 01, 2018 |
| Contact name |
Li Wang |
| Organization name |
Icahn school of medicine at Mount Sinai
|
| Street address |
1 Gustave L. Levy Pl
|
| City |
New York |
| ZIP/Postal code |
10029 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL22245 |
Illumina HiSeq 2500 (Homo sapiens; Mus musculus) |
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| Samples (15)
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| Relations |
| BioProject |
PRJNA477510 |
| SRA |
SRP151120 |
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