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Series GSE116061 Query DataSets for GSE116061
Status Public on Jun 21, 2018
Title Modified penetrance of coding variants by cis-regulatory variation contributes to disease risk
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary Edited mendelian disease SNP rs199643834 responsible for Birt-Hogg-Dubé Syndrome into 293T cells using CRISPR/Cas9
Overall design Human 293T cells were edited using CRISPR/Cas9 and a homologus template containing the desired SNP. Monoclonal lines were generated and genotyped.
Contributor(s) Castel SE, Lappalainen T
Citation(s) 30127527
Submission date Jun 20, 2018
Last update date Nov 05, 2018
Contact name Stephane Emile Castel
Organization name New York Genome Center
Lab Lappalainen
Street address 101 Avenue of the Americas
City New York
State/province NY
ZIP/Postal code 10013
Country USA
Platforms (1)
GPL24676 Illumina NovaSeq 6000 (Homo sapiens)
Samples (13)
GSM3208198 HEK293T_rs199643834_EDIT_WT [4_38]
GSM3208199 HEK293T_rs199643834_EDIT_WT [4_75]
GSM3208200 HEK293T_rs199643834_EDIT_WT [7_60]
BioProject PRJNA476937
SRA SRP150991

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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE116061_flcn_clones_gene_counts.txt.gz 882.1 Kb (ftp)(http) TXT
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Processed data are available on Series record

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