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Series GSE115440 Query DataSets for GSE115440
Status Public on Nov 13, 2018
Title Maresin 1 attenuates neuroinflammation in a mouse model of perioperative neurocognitive disorders
Organism Mus musculus
Experiment type Expression profiling by array
Summary Maresin 1 administered to mice prior to orthopedic surgery exerts distinct anti-inflammatory and pro-resolving effects through regulation of MΦ infiltration, NF-κB signaling, and cytokine release.
We used microarrays to detail the global programme of gene expression underlying Maresin 1 effect on mouse hippocampus and identified distinct classes of dysregulated genes during this process.
Overall design Mice hippocampi were isolated 72 h after surgery and RNA was extracted for further processing and hybridization on Affymetrix microarray.
Web link
Contributor(s) Mkrtchian S, Terrando N
Citation(s) 30770053, 35116043
Submission date Jun 07, 2018
Last update date Feb 08, 2022
Contact name Souren Mkrtchian
Phone +46739586763
Organization name Karolinska Institutet
Department Physiology and Pharmacology
Lab Section of Anesthesiology
Street address Solnavägen 9
City Stockholm
ZIP/Postal code 17177
Country Sweden
Platforms (1)
GPL11533 [MoGene-1_1-st] Affymetrix Mouse Gene 1.1 ST Array [transcript (gene) version]
Samples (9)
GSM3178275 Control mouse, biological rep1
GSM3178276 Control mouse, biological rep2
GSM3178277 Control mouse, biological rep3
BioProject PRJNA475007

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE115440_RAW.tar 42.0 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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