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| Status |
Public on May 21, 2024 |
| Title |
Genome wide analysis of lower spinal cords with training after spinal cord hemisection injury |
| Organism |
Rattus norvegicus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
The goal of this study is to elucidate the influence of treadmill training on transcriptome of the lower lumbar spinal cord after thoracic spinal cord hemisection. mRNA profiles of spinal cords at 23 days-post injury with/without treadmill training were generated. The expression levels of 650 genes in the trained animal were increased ( > 2-fold) compared to untrained animals. Our study represents the detailed analysis of transcriptomes of spinal cord distal to the hemisected lesion after treadmill training, with biologic replicates, generated by RNA-seq technology.
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| Overall design |
The effect of training after spinal cord injury (T9) on the transcriptome of intact lower spinal cord was investigated.
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| Contributor(s) |
Kobayakawa K, Edgerton R, Harada A, Nogami J, Ohkawa Y |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Jun 01, 2018 |
| Last update date |
May 21, 2024 |
| Contact name |
Yasuyuki Ohkawa |
| E-mail(s) |
yohkawa@bioreg.kyushu-u.ac.jp
|
| Organization name |
Medical Institute of Bioregulation
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| Lab |
Division of Transcriptomics
|
| Street address |
3-1-1 Maidashi
|
| City |
Fukuoka |
| ZIP/Postal code |
8128582 |
| Country |
Japan |
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| Platforms (1) |
| GPL18404 |
Illumina HiSeq 1500 (Rattus norvegicus) |
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| Samples (8)
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| Relations |
| BioProject |
PRJNA474208 |
| SRA |
SRP149799 |
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